IARR Distinguished Scientist Award 2019
Professor Dudley Goodhead
We are delighted to announce that Professor Dudley Goodhead will be presented the 2019 International Association for Radiation Research Henry S. Kaplan Distinguished Scientist Award in Manchester.
ICRU Twentieth Gray Medal
Doctor Eleanor Blakely
The ICRU is pleased to announce that the Twentieth Gray Medal will be presented to Dr. Eleanor Blakely at the 16th International Congress of Radiation Research in Manchester, UK, in August 2019.
Professor Goodhead obtained his Ph.D. in Particle Physics at the University of Oxford. His research focused on elucidating the radiation track structure at the atomic, molecular, and cellular levels and their consequent radiobiological and health effects. He demonstrated an exceptional ability to integrate biophysical studies with cellular consequences, providing insight into how radiation damages our DNA and its impact on repair. Exploiting these extraordinary interdisciplinary skills, he has been a pioneer in the field of radiation biophysics and radiobiology.
Professor Goodhead was a highly respected Director of the Medical Research Council’s Radiation and Genome Stability Unit, Harwell, U.K. He has additionally served on many national and international committees evaluating radiation risks, including UK’s Committee on Medical Aspects of Radiation in the Environment, National Research Council, the National Council on Radiation Protection and Measurements and multiple working groups of the International Agency for Research on Cancer. He was a consultant for UNSCEAR and IAEA. He was chair of the United Kingdom’s Committee Examining Radiation Risks of Internal Emitters and of the Advisory Group on Ionizing Radiation of Public Health. In the 2002 Queen’s Birthday Honours List, he was awarded the Order of the British Empire for services to medical research.
Professor Dudley Goodhead will be presented the 2019 International Association for Radiation Research Henry S. Kaplan Distinguished Scientist Award in Manchester. The purpose of the award is to honour outstanding contributions to the field of radiation research. Any scientist who has made superior contributions to the field through investigations in physics, chemistry, biology or medicine is eligible. Professor Goodhead has pioneered work across these fields in radiation biophysics and radiobiology.
Additional awards include the Weiss Medal from the ARR, the Failla Medal from the Radiation Research Society, the Douglas Lea Lecturer from the Institute of Physics and Engineering in Medicine and Biology, the Bacq & Alexander Award from the European Society of Radiation Biology, an Honorary Fellowship from the Society of Radiological Protection, the Warren K. Sinclair Award from the NCRP, and the Gray Medal from the International Commission on Radiation Units and Measurements. Professor Goodhead and his work continues to be extremely well respected and an inspiration to many.
Dr. Blakely was born in Quantico, VA, and attended the University of San Diego, San Diego, CA where she received a B.A. degree in Biology. She completed a M.S. degree in Biophysics, and a Ph.D. in Physiology at the University of Illinois, Champaign-Urbana, IL as a U.S. Atomic Energy Commission Special Fellow in Radiation Science and Protection in the laboratory of Professor Howard Ducoff. She participated in radiobiology training at three U.S. Department of Energy (DOE) Laboratories: Oak Ridge National Laboratory, Knoxville, TN with Dr. Frank Comas, Lawrence Berkeley Laboratory (LBL), Berkeley, CA with Dr. John Leith in the laboratory of Professor Cornelius Tobias, and Argonne National Laboratory, Lemont, IL with Dr. Warren Sinclair.
Upon graduation, Dr. Blakely returned to LBL as a Staff Scientist working directly with Professor Cornelius Tobias and with Drs. Joseph Castro and Theodore Phillips conducting pre-clinical investigations, and Phase I/II trials with heavy charged particle radiotherapy. Since 1989, Dr. Blakely has been a Senior Staff Biophysicist at the Lawrence Berkeley National Laboratory (LBNL) with more than 40 y of professional experience in molecular, cellular and animal radiobiological research directed at studying the basic mechanisms of radiation responses, with an emphasis on charged particle radiation effects. She also holds a Faculty Affiliate Appointment in the Department of Radiological Health Sciences at Colorado State University, Fort Collins, CO and is a Clinical Professor of Radiation Medicine (nontenured) at Loma Linda University, School of Medicine, Loma Linda, CA. She has published over 100 peer-reviewed papers and several book chapters.
Her professional activities included service on a variety of advisory panels for several hospitals, universities, and numerous federal agencies including the U.S. Department of Energy, the National Institutes of Health (NIH), National Aeronautics and Space Administration (NASA) and the Department of Defense (DOD). She is an Appointed Member for the Diagnostic Radiology Study Section-Division of Research Grants, NIH; Advisory Committee Member for the International Atomic Energy Agency (IAEA); She was elected as the councilor representing the Biology discipline (1984-1987) and the Secretary-Treasurer for the Radiation Research Society (RRS) (2011-2017). She continues to serve on Editorial Boards for several journals: Radiation Research, Journal of Radiation Research and npj Microgravity.
She has a long-standing relationship with NCRP. In 2000 she was elected to NCRP and served on Scientific Committee (SC) 75 that produced NCRP Report No. 132, Radiation Protection Guidance for Activities in Low-Earth Orbit; and SC 1-7 that produced NCRP Report No. 153, Information Needed to Make Radiation Protection Recommendations for Space Missions Beyond Low-Earth Orbit. In 2011, she was named the NCRP 35th Lauriston S. Taylor Lecturer. Dr. Blakely co-chaired NCRP SC 1-23 that produced NCRP Commentary #26- Guidance on Radiation Dose Limits for the Lens of the Eye (2016).
In addition to being an outstanding scientist, she has received number awards in teaching and mentoring young scientists including the Robert Emerson Graduate Teaching Award, School of Life Sciences, University of Illinois, the LBL Outstanding Performance Award, the DOE Office of Science Outstanding Mentor Award, and the LBL Technology Transfer Award. She was appointed the Scientific Director of the NASA Space Research Summer School for two consecutive years (2007-2008), and received an RD100 award from Research and Development Magazine (2005). She was awarded the Martin Schneider Memorial Lectureship, University of Texas Medical Branch, Galveston, Texas. In June 2015 she retired after 40 years at LBNL, but was rehired by LBNL in October 2015, and continues to work part-time. Dr. Blakely received the Berkeley Laboratory Director’s Award for Exceptional Achievement: the Berkeley Lab Citation Award (2015), was named a Fellow of the American Association for the Advancement of Science (2016), received the Distinguished Service Award of the RRS (2017), and was named a Distinguished Emeritus Member of the NCRP (2018).
ARR Weiss Medal
Professor Penny Jeggo
The ARR is pleased to announce that the ARR Weiss Medal for 2019 will be presented to Penny Jeggo at the 16th International Congress of Radiation Biology in Manchester, UK in August 2019.
Bacq and Alexander Award
Penelope (Penny) A Jeggo graduated in microbiology at Queen Elizabeth College, University of London and obtained a PhD in Genetics in Robin Holliday’s laboratory at the National Institute for Medical Research, Mill Hill, London. She then undertook Post Doctoral fellowships with John Cairns at the Imperial Cancer Research Fund and Miroslav Radman at the Universite Libre de Bruxelles, Belguim, before returning in 1980 to Robin Holliday’s laboratory and commencing work on the DNA damage responses in mammalian cells. In 1989 she moved to the MRC’s Cell Mutation Unit at the University of Sussex and when the Unit closed in 2001 became a founding member of the Genome Damage and Stability Centre (GDSC) at the University of Sussex. She became a Professorial Fellow of the University of Sussex in 2003.
Prof Jeggo’s early work focused on studying DNA damage responses in lower organisms but subsequently focused on the process of DNA double strand break (DSB) repair in mammalian cells. She isolated radiosensitive, DSB-repair defective (Xrs) mutants from the CHO cell line, which have been exploited by many colleagues to study DNA DSB. In 2004 the Xrs mutants were shown to be mutated in Ku80, identifying the first gene involved in DNA non homologous end joining (NHEJ) as well as the development of the immune response. Subsequently, she showed that the gene mutated in the Severe Combined Immunodeficient (SCID) mouse encodes the DNA dependent protein kinase, DNA-PKcs, which together with Ku forms the DNA-PK complex. These findings consolidated the notion that in mammalian cells DSBs are repaired by a process distinct from homologous recombination and paved the way for our understanding of NHEJ. They also revealed the important role that NHEJ plays during immune development. A search for radiosensitive immunodeficient patients led to the identification of LIG4 Syndrome, the first of several human disorders with combined defects in DNA DSB repair and V(D)J recombination. Work in the GDSC contributes to the diagnosis of such patients, which is important for the optimisation of their care and treatement.
Throughout her research career, Penny has had a deep interest in radiation biology, radiation protection and the exploitation of radiation for radiotherapeutic and diagnostic purposes. Penny has served as a member of an international laboratory at the National Institute for Radiation Science in Chiba, Japan. She has been a member of ICRP and AGIR subgroups evaluating radiation effects, a member of the Committee on Medical Aspects of Radiation in the Environment (COMARE), participated in the MELODI programme and was a previous chair of UK’s ARR. She has been a member of the Scientific Advisory Committee of the EMF Biological Research Trust and CRUK’s Science Funding Committee. She has been elected as a Fellow of the Academy of Medical Sciences. She is on the Editorial board of several journals including DNA Repair and International Journal of Radiation Biology. She has more than 200 publications. She believes a career in science can be fun and rewarding and is keen to aid the advancement of scientists in training (SITS) and women in science.
Markus Löbrich studied Physics at the Justus-Liebig-University in Gießen, Germany, and obtained his Ph.D. in Jürgen Kiefer’s lab in the field of Radiation Biophysics. He performed part of his Ph.D. work on a DAAD Fellowship at the Lawrence Berkeley National Laboratory in Berkeley, CA, USA, in the group of Priscilla Cooper and joined the same group as a Postdoctoral Researcher afterwards. After returning to Germany, he set up his own lab, was promoted to Assistant Professor and obtained his habilitation. He then moved as an Associate Professor for Molecular Radiation Biology to the Medical Faculty of the Saarland University in Homburg, Germany. After his promotion to Full Professor, he accepted an offer to establish a Radiation Biology and DNA Repair group at the Darmstadt University of Technology in Darmstadt, Germany, where he currently works.
During his early work, Markus concentrated on elucidating differences in the mechanisms of DNA double-strand break repair between various radiation types, with a focus on the analysis of radiation-induced genomic rearrangements. His career was boosted during his time in Homburg, where he discovered together with his co-worker Kai Rothkamm that DNA double-strand break repair after low dose irradiation proceeds less efficiently than after high dose irradiation, a ground-breaking finding that has hitherto been cited more than 1000 times and paved the way for many subsequent studies. Markus also utilized together with his collaborator Michael Uder the technical ability to assess low dose radiation damage to evaluate exposure levels in humans undergoing various radiological examinations. Markus’ subsequent studies focused on the molecular mechanisms of double-strand break repair, where he discovered together with his colleague Penny Jeggo that a class of double-strand breaks is intrinsically difficult to repair. His recent work mechanistically unravels the molecular steps of non-homologous end-joining and homologous recombination, exploring the possibility that RNA can be employed by the cellular repair system to maintain genomic integrity.
Markus has received numerous awards for his work, including the Hanns-Langendorff-Award of the German Association of Medical Doctors for Radiation Protection, the Friedrich-Dessauer-Award of the Committee for Radiation Research in Germany and the Michael-Fry-Research-Award of the American Radiation Research Society. He served as the President of the German Society for Biological Radiation Research and as the Vice President of the German Society for Research on DNA Repair. He was appointed member of the Executive Committee of the National Radiation Protection Board and the Committee for Radiation Risk. Markus has been heading the first German Gradual School on Radiation Research which involves the training of nearly 100 Ph.D. students and is supported by the German Research Foundation. He hopes that this endeavor will help to keep the field of Radiation Research flourishing for the next decades.
Markus will be presented with the Bacq and Alexander Award by the European Radiation Research Society (ERRS, www.errs.eu) at ICRR2019 in Manchester. Since 1996, the ERRS has presented the Bacq and Alexander award each year to an outstanding European researcher to recognise their achievements in the field of radiation research. This year’s award will honour Markus‘ pioneering work and his outstanding contributions to the field of radiation research.